In Greek mythology, Polydorus referred to three different people.
- Son of Hippomedon and one of the Epigonoi.
- Son of Cadmus and Harmonia, father of Labdacus
- King Priam's youngest son during the Trojan War, he was sent with gifts of jewelry and gold to the court of King Polymestor to be kept safe during the Trojan War. The fighting was getting vicious and Priam was frightened for the child's safety. After Troy fell, Polymestor threw Polydorus to his death to take the treasure for himself. Hecuba, Polydorus' mother, eventually avenged her son.