1. HRH Prince Frederick Lewis (or Frederick Louis) (1707-1751), eldest son of The Prince of Wales, (from 1727) Prince of Wales. 1726-1751
2. HRH Prince George (1738-1820), eldest son of the first Duke, (from 1751) Prince of Wales and (from 1760) King George III. 1751-1760

Second Creation, November 19, 1764(Great Britain)

1. HRH Prince William of Wales (1743-1805), younger brother of King George III
2. HRH Prince William of Gloucester (1776-1834), son of the first duke.

Third Creation, May 24, 1866 (United Kingdom)

1. HRH Prince Alfred (1844-1900), second son of Queen Victoria, (from 1893) Duke Alfred of Saxe-Coburg-Gotha.

Fourth Creation, November 20, 1947 (United Kingdom)

1. Philip Mountbatten (1921- ), formerly HRH Prince Philip of Greece and Denmark

Note: Although it was announced at the time of the wedding of Prince Edward that he would eventually receive this title, he will not inherit the title from his father. Like any normal dukedom, the present Dukedom of Edinburgh passes to the heirs-male of the first Duke. That means that when the present Duke dies, the dukedom will be inherited by his eldest son, The Prince of Wales. If The Prince of Wales is not yet king when this occurs, he will be Duke of Edinburgh until he ascends the throne, at which point the title will merge with the crown, like any title borne by the King. Only at that point would the title be available for regrant to the Earl of Wessex.